My love affair with Greg Iles's work began this year after taking a chance on his Penn Cage series. The story about how I stumbled upon his work is laid out in gloriously laborious detail in my review.
I have since read the next two books in the series, Turning Angel and The Devil's Punchbowl, and have finally arrived at the book that made me want to read this series to begin with -- Natchez Burning. The Penn Cage books continue to exceed my expectations and have quickly become my favorite non-continuous-storyline series.
If you haven't read anything by Iles, I suggest you start with The Quiet Game.